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Dr Efevretis's avatar

The strongest turn in this is moving from the single PPI to the approval framework, because that 2018 screen you cite reframes the whole question. If roughly a quarter of human-targeted drugs already inhibit a gut strain, then microbiome impact isn't a fringe effect, it's a routine one that simply wasn't being measured. The liver-kidney-heart comparison is apt: we monitor what the approval pipeline was built to see, and the microbiome sat outside that frame, so the effects only surface once millions are already taking the drug.

MitoExplorer's avatar

Dose that mean that some medications can do more harm than good ?

Lorene Sauro's avatar

It depends on the person and the state of their gut. But if they really need the medication, then the answer is to protect the gut and other areas of the body to lessen any potential harm - we have the knowledge for this - it can be done.

MitoExplorer's avatar

I took Levothyroxine and I believe it ruined my gut health and was only providing T4 for me

Do you know of any Holistic Thyroid medication that has T1,T2 and T3 ?

Or a good gut health test and Hormone test ?

Lorene Sauro's avatar

Hi. There's no evidence that Levothyroxine harms gut microbes, but it is more complicated than this, depending on the state of the gut when the person starts taking Levothyroxine. I do offer gut testing as one of my services, depending on where you live, but you may want to see a naturopath for the hormone test and T1, T2 & T3. I know T3 is available, but the naturopath would know best what you should. They can also proabably do gut testing.